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Blood group compatibility chart

For red cells, O negative can be given to every group and AB positive can receive from every group. For plasma it reverses: AB plasma suits every group and group O patients can receive plasma from anyone. Every transfusion still needs a crossmatch on the patient's own sample.

Choose the patient's blood group:

O−O+A−A+B−B+AB−AB+

Red cell compatibility, group by group

PatientCan receive red cells from
O−O−
O+O−, O+
A−O−, A−
A+O−, O+, A−, A+
B−O−, B−
B+O−, O+, B−, B+
AB−O−, A−, B−, AB−
AB+All eight groups

Plasma compatibility

PatientCan receive plasma from
OO, A, B, AB
AA, AB
BB, AB
ABAB only

Plasma carries antibodies rather than red cells, so the rules run the other way round. Rh group is not a concern for plasma.

What about platelets and rare groups?

Platelets are best given ABO-identical. When that is not available, local policy decides; Rh-negative girls and women of child-bearing age should receive Rh-negative platelets where possible. People with the rare Bombay phenotype can receive red cells only from other Bombay donors.

This chart explains the general rules. It is not a substitute for grouping, antibody screening and crossmatch on the patient's current sample, or for your blood centre's SOP.

How does blood bank software use these rules?

Caresoft BBMS applies these rules automatically. When a patient is grouped, it offers only compatible units, earliest expiry first, and refuses to issue any bag that does not match, including in emergencies, where only O negative red cells or AB plasma are allowed.

See BBMS block an incompatible issue

Questions people ask

Which blood group is the universal donor?
For red cells, O negative is the universal donor because its red cells carry no A, B or D antigens. For plasma, AB is the universal donor.
Which blood group is the universal recipient?
For red cells, AB positive patients can receive from all eight groups. For plasma, group O patients can receive any ABO group.
Can an Rh-positive person receive Rh-negative blood?
Yes. Rh-positive patients can receive Rh-negative red cells. The reverse is avoided, especially for girls and women who may become pregnant.
Is a compatibility chart enough before transfusion?
No. The chart shows general rules only. Each patient needs grouping, an antibody screen and a crossmatch on a fresh sample before red cells are issued.

See it with your own stock and workflow

A 30-minute demo walks through donor to bedside, the safety stops, and how BBMS connects to your HIS.